Trial Search Results

Comparing Effects of 3 Sources of Garlic on Cholesterol Levels

The purpose of this study is to determine whether fresh garlic can positively affect cholesterol in adults with moderately high cholesterol levels. This study will also determine whether the same effects can be found for two main types of garlic supplements: a dried powdered garlic (designed to yield the same effect as fresh garlic) and an aged garlic extract preparation.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

National Center for Complementary and Integrative Health (NCCIH)

Collaborator: Office of Dietary Supplements (ODS)

Stanford Investigator(s):

Intervention(s):

  • Drug: Fresh garlic or garlic supplements

Phase:

Phase 2/Phase 3

Eligibility


Inclusion Criteria:

   - LDL-C 130-190 mg/dL (fasting single sample)

   - BMI (body mass index) 19-30 kg/m2 (42-66 lb/m2)

   - Weight stable for last 2 months

   - Not actively on a weight loss plan

   - Ethnicity representative of local population

   - No plans to move from the area over the next 9 months

Exclusion Criteria:

   - Pregnant, lactating, within 6 months postpartum, or planning to become pregnant in the
   next year

   - Diabetes (type I or II) or history of gestational diabetes

   - Heart disease

   - Active neoplasms

   - Renal or liver disease

   - Hyperthyroidism or hypothyroidism

   - Lipid lowering medications (known to affect lipid metabolism, platelet function, or
   antioxidant status)

   - Blood pressure medications

   - Excessive alcohol intake (self reported, more than 3 drinks/day)

   - Currently under psychiatric care or severely clinically depressed

Ages Eligible for Study

30 Years - 65 Years

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Not Recruiting