Reproductive Function and Mood in Women With Bipolar Disorder

Inclusion Criteria for All Participants:

   - Have been menstruating for at least 4 years prior to study entry

   - Participants must be willing to travel to Stanford University at own expense for study
   visits

Inclusion Criteria for Bipolar Disorder Participants:

   - Participants should have a diagnosis of Bipolar I, Bipolar II, or Bipolar not
   otherwise specified (NOS), and be under the treatment of a physician who can be
   contacted in case of an emergency

   - Current treatment with any mood-stabilizing agent for a period of at least 3 months
   (e.g., divalproex sodium, lithium, other mood stabilizer, or atypical antipsychotic)

Inclusion Criteria for Healthy Controls:

   - No past or present diagnosis of mental illness

Exclusion Criteria for All Participants:

   - Current alcohol or substance abuse or dependence within 6 months prior to study entry

   - Meets criteria for another DSM-IV Axis I disorder

   - Contraceptive steroid use within 3 months prior to study entry

   - Current use of medication that may affect steroid metabolism

   - Menopausal

   - Endocrine disease such as diabetes or hypothyroidism

   - Uncontrolled medical illness

   - History of long-term corticosteroid use

   - Organic mood disorder

   - Pregnancy or breastfeeding within 3 months prior to study entry