Trial Search Results

Duloxetine for the Treatment of Dysthymia

The purpose of this study is to test the hypothesis that duloxetine (Cymbalta), in doses of 60 or 120 mg/day, is an effective and tolerable treatment for adult outpatients suffering from dysthymia. Dysthymia is chronic, mild depression characterized by feeling sad or low more days than not for more than 2 years.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University

Collaborator: Eli Lilly and Company

Stanford Investigator(s):

Intervention(s):

  • Drug: duloxetine

Phase:

N/A

Eligibility


Inclusion Criteria::

   - Sign an informed consent form

   - 18 years of age or older

   - Females not pregnant or breastfeeding or planning pregnancy and using an acceptable
   form of contraception

   - Meet DSM-IV criteria for dysthymia

   - A screening IDS-C score of 17 or greater

   - No history of serious or unstable medical disorder

   - Not taking any significant concurrent medications

   - Not currently receiving psychotherapy

Exclusion Criteria:- Suffering from DSM-IV defined

   - delirium, dementia, amnestic, or other cognitive disorders

   - mental disorders due to a general medical condition

   - factitious or somatoform disorders

   - mental retardation or developmental disabilities

   - substance or alcohol abuse within the last 3 months

   - depressive disorders with current suicidal risk

   - psychotic disorders including delusional disorder, somatic type

   - dissociative disorder

   - personality disorders sufficiently severe to interfere with study participation

   - History of DSM-IV defined bipolar I or II disorder

   - History of non-response of dysthymia to adequate antidepressant medication

   - History of major depression refractory to two adequate trials of antidepressants

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Nona Gamel
6507255180
Not Recruiting