Trial Search Results

A Trial of Thalidomide and Capecitabine in Metastatic Renal Cell Carcinoma

The purpose of this study is to determine the efficacy of the combination of thalidomide and capecitabine in metastatic renal cell carcinoma and also to determine the safety of the combination.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University

Collaborator: Celgene Corporation

Stanford Investigator(s):

Intervention(s):

  • Drug: Thalidomide
  • Drug: Capecitabine

Phase:

Phase 2

Eligibility


Inclusion Criteria:- Able to comprehend and sign an IRB approved Informed consent

   - Willingness and ability to comply with the FDA-mandated S.T.E.P.S.® program.

   - Male or female 18 years or older

   - Willing to use contraception

   - Pathologic diagnosis of renal cell carcinoma

   - Bi-dimensionally measurable disease

   - Evidence of disease progression prior to start of treatment

   - Failed prior immunotherapy or unwilling/unable to receive prior immunotherapy

   - Adequate hematologic data: ANC.1.5; platelets>100x10^9

   - Adequate renal function: Creatinine clearance .50cc

   - Adequate liver function: Alkaline phos <3XULN AST/ALT <3XULN T.Bili <1.5XULN

   - ECOG performance status 0-1

Exclusion Criteria:- Known brain metastases.

   - Peripheral neuropathy.

   - Pregnant and/ or lactating female.

   - Unable to take a baby aspirin.

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Denise Haas
6507361252
Not Recruiting