Trial Search Results

Modafinil Treatment for Sleep/Wake Disturbances in Older Adults

Modafinil, trade named Provigil, is a medication approved by the Food and Drug Administration for the treatment of narcolepsy, obstructive sleep apnea/hypopnea syndrome, and shift work sleep disorder. Each of these problems is characterized by difficulty sleeping at night and excessive daytime sleepiness. Modafinil is prescribed during the day to counteract this sleepiness. The idea behind this treatment is that sleepiness that leads to napping during the day prevents a patient from being tired or sleepy enough to get good sleep at night. This study is designed to determine if the medication can "reset" participants' sleep/wake rhythm to a more normal rhythm.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

VA Palo Alto Health Care System

Stanford Investigator(s):

Intervention(s):

  • Drug: modafinil

Phase:

Phase 4

Eligibility


Inclusion Criteria:

   - A clinical diagnosis of Alzheimer's disease or Mild Cognitive Impairment

   - Subjective complaint of sleep disruption, unsatisfactory sleep, early morning
   awakening, early bedtime, or excessive daytime sleepiness. Such complaint can be made
   by either the potential participant or by the caregiver.

Exclusion Criteria:

   - Participation in any other clinical drug trial

   - Liver failure

   - Believed by the investigator to be unwilling or unable to follow the protocol

   - Active liver or coronary disease

Ages Eligible for Study

50 Years - N/A

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Ban Ku
6508491971
Not Recruiting