Trial Search Results
Effect of IV Lidocaine Infusions on Pain
Our goals for this study involve using intravenous lidocaine as it is normally used in the Stanford Pain Management Center to assess the effect of intravenous lidocaine on chronic pain. Studies have been done determining the efficacy of intravenous lidocaine for treating pain but little research has been done to determine the effects of an intravenous lidocaine infusion on the different components of the pain experience. Our study will incorporate pain quality measures both before and during the infusions of lidocaine to determine changes in present pain intensity.
Stanford is currently not accepting patients for this trial.
- Drug: Intravenous lidocaine
Inclusion Criteria:- subjects between the ages of 18 and 100 years for clinical component;
subjects between the ages of 18 and 70 for the MRI component
- meets the study criteria of chronic pain of either peripheral or central origin
- male or a non-pregnant, non-lactating female. If females are of reproductive potential
(i.e., not surgically sterilized and/or not post menopausal), they must be practicing
an accepted method of birth control, agree to a urine pregnancy test at the start of
each study session (for patient scheduled through the clinic, this has already been
addressed by the recommending physician)
- is not currently on a sodium channel blocking agent, anticonvulsant, or tricyclic
- must be able to comply with any other study requirements and complete experimental
- have no reported substance abuse within the past six months;
Exclusion Criteria:- subject is lactating or pregnant;
- subject suffers from clinically significant cardiac, pulmonary, renal or liver
- subject allergic to lidocaine.
- MRI Component: any metal objects (especially surgical clips), devices, or implants or
any other MRI contraindication
Ages Eligible for Study
18 Years - 100 Years
Genders Eligible for Study