Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples

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Trial ID: NCT01034033

Purpose

The purpose of this study is to try to understand the biology of development of breast, ovarian, fallopian tube, peritoneal or endometrial cancer from persons at high genetic risk for these diseases. The influence of environmental factors on cancer development in individuals and families will be studied. The efficacy of treatments for these diseases will be evaluated.

Official Title

Genetic & Pathological Studies of BRCA1/BRCA2: Associated Tumors & Blood Samples

Stanford Investigator(s)

James Ford
James Ford

Professor of Medicine (Oncology) and of Genetics and, by courtesy, of Pediatrics

Allison W. Kurian, M.D., M.Sc.
Allison W. Kurian, M.D., M.Sc.

Professor of Medicine (Oncology) and of Epidemiology and Population Health

Jafi Alyssa Lipson
Jafi Alyssa Lipson

Clinical Associate Professor, Radiology

Jonathan S. Berek, MD, MMSc
Jonathan S. Berek, MD, MMSc

Laurie Kraus Lacob Professor

Eligibility


Inclusion Criteria:

I. Women who have a high risk of developing breast or ovarian cancer due to a known
germline mutation in the BRCA1/2, PTEN, CDH1, or TP53 cancer susceptibility genes, or due
to strong family history of either breast or ovarian cancer, in the absence of known cancer
susceptibility gene mutation.

II. Women who are approaching surgery for resection of a pelvic mass, which is considered
suspicious for neoplasia by radiologic or clinical criteria; such women may or may not also
meet criteria for inclusion in group I.

Recruiting

I'm Interested

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Meredith Mills
650-724-5223

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