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A Comprehensive Study to Isolate Tumor-initiating Cells From Human Epithelial Malignancies
Not Recruiting
Trial ID: NCT01060319
Purpose
We hypothesize that all human malignancies harbour a subpopulation of tumor initiating
cells/cancer stem cells (CSCs) that drives tumor development and potentially recurrence or
metastasis of the disease. The primary aim of this study is to develop strategies for
prospective isolation/enrichment of CSCs from human tumors of different tissue origins. In
addition, we will characterize the signaling pathways and/or tumor specific antigens that are
specific for CSCs, in order to specifically target these CSCs as the endpoint of this study.
Official Title
A Comprehensive Study to Isolate Tumor-initiating Cells From Human Epithelial Malignancies
Stanford Investigator(s)
Eligibility
Inclusion Criteria:N/A. We will recruit all non-melanoma skin and bladder cancer patients
that are recommended for surgical removal of tumor tissues. This includes patients from all
ages, gender and ethnicity background. Our sample collection criteria based on the tumor
size of individual (e.g. tumor samples will only be collected if it will not affect the
pathological diagnosis or treatment procedures of patients). Exclusion Criteria:N/A
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Linda Quinn
650-723-6520