Trial Search Results

Stanford Accelerated Recovery Trial (START)

The goal of this study is to determine whether administering Gabapentin prior to surgery affects duration of pain and opioid use post-surgery. The investigators aim to compare gabapentin to placebo in a prospective, randomized clinical trial in which patients will be followed post-surgery until pain resolves and opioid use ceases.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University

Stanford Investigator(s):


  • Drug: Gabapentin
  • Drug: Placebo


Phase 3


Inclusion Criteria:

   1. Age 18-75

   2. Undergoing a scheduled surgery

   3. English speaking

   4. Ability and willingness to complete questionnaires or use palm pilot

Exclusion Criteria:

   1. Known kidney disease

   2. On gabapentin or (pregabalin) lyrica already

   3. Cognitive impairment

   4. Previous history of excessive sedation or adverse reaction to gabapentin (not it was
   tried but ineffective for nerve pain)

   5. Coexisting chronic pain >4/10 disorder in area other than surgical target

   6. Plan to move out of state

   7. Condition that would in judgment of team member make patient likely to be lost to
   follow up

   8. elevated Suicidality

   9. Known pregnancy

10. Current symptoms of ataxia, dizziness, or sedation

11. Narrow angle glaucoma

12. Severe respiratory insufficiency (i.e. severe emphysema or chronic obstructive
   pulmonary disease)

13. History of gastric bypass surgery and obstructive sleep apnea requiring CPAP

Ages Eligible for Study

18 Years - 75 Years

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305