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Prevention of Altitude Illness With Non-steroidal Anti-inflammatory Study (PAINS)
Not Recruiting
Trial ID: NCT01171794
Purpose
This is a research study on Altitude Illness. From the information collected and studied in
this project we hope to learn more about Altitude Illness, including factors that may affect
and prevent the development and progression of this condition. We hope to learn if the
commonly used non-steroidal anti-inflammatory medication, ibuprofen can prevent altitude
illness. Possible participants in this study are healthy adults who indicated they would like
to participate, learn about altitude illness, and desire to hike Barcroft Peak. Stanford
University researchers hope to enroll about 100 participants.
Official Title
Prevention of Altitude Illness With Non-steroidal Anti-inflammatory Study (PAINS)
Eligibility
Inclusion Criteria:
1. Healthy Male or female volunteer
2. Age 18-65
3. Sea-level dwelling
4. Non pregnant
5. Have not been to high altitude in the past week
6. Can arrange for their own transportation to WMRS by friday evening the weekend of
their study enrollment and are available the duration of the weekend of their study
enrollment
Exclusion Criteria:
1. Age <18 or >65
2. Live at altitude > Sea Level +/- 1000'
3. Pregnant
4. Taking NSAIDs, Acetazolamide, or Corticosteroids
5. Allergic to NSAIDs or Aspirin, or have had adverse reaction to them in the past
6. Traveled or planning to travel to high altitude in the week prior to their enrollment.
7. Medical history of Brain Tumor, increased intercranial pressure, pseudotumor cerebri,
ventricular shunts, loss of an eye, Asthma, HACE or HAPE.
8. Cannot arrange for their own transportation to WMRS or are unavailable for the
duration of the weekend of their study enrollment
Intervention(s):
drug: Ibuprofen
drug: Placebo
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Grant Lipman
6507236576