Trial Search Results

Prevention of Altitude Illness With Non-steroidal Anti-inflammatory Study (PAINS)

This is a research study on Altitude Illness. From the information collected and studied in this project we hope to learn more about Altitude Illness, including factors that may affect and prevent the development and progression of this condition. We hope to learn if the commonly used non-steroidal anti-inflammatory medication, ibuprofen can prevent altitude illness. Possible participants in this study are healthy adults who indicated they would like to participate, learn about altitude illness, and desire to hike Barcroft Peak. Stanford University researchers hope to enroll about 100 participants.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University

Collaborator: University of California, San Diego

Stanford Investigator(s):

Intervention(s):

  • Drug: Ibuprofen
  • Drug: Placebo

Phase:

Phase 3

Eligibility


Inclusion Criteria:

   1. Healthy Male or female volunteer

   2. Age 18-65

   3. Sea-level dwelling

   4. Non pregnant

   5. Have not been to high altitude in the past week

   6. Can arrange for their own transportation to WMRS by friday evening the weekend of
   their study enrollment and are available the duration of the weekend of their study
   enrollment

Exclusion Criteria:

   1. Age <18 or >65

   2. Live at altitude > Sea Level +/- 1000'

   3. Pregnant

   4. Taking NSAIDs, Acetazolamide, or Corticosteroids

   5. Allergic to NSAIDs or Aspirin, or have had adverse reaction to them in the past

   6. Traveled or planning to travel to high altitude in the week prior to their enrollment.

   7. Medical history of Brain Tumor, increased intercranial pressure, pseudotumor cerebri,
   ventricular shunts, loss of an eye, Asthma, HACE or HAPE.

   8. Cannot arrange for their own transportation to WMRS or are unavailable for the
   duration of the weekend of their study enrollment

Ages Eligible for Study

18 Years - 65 Years

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Grant Lipman
6507236576
Not Recruiting