Trial Search Results

Biomarkers in Blood Samples From Young Patients With Newly Diagnosed Brain Tumors Undergoing Standard Radiation Therapy and Chemotherapy

RATIONALE: Studying samples of blood in the laboratory from patients receiving radiation therapy and chemotherapy may help doctors learn more about the effects of this treatment on cells. It may also help doctors understand how well patients respond to treatment.

PURPOSE: This research study is studying biomarkers in blood samples from young patients with newly diagnosed brain tumors undergoing standard radiation therapy and chemotherapy.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Pediatric Brain Tumor Consortium

Collaborator: National Cancer Institute (NCI)

Stanford Investigator(s):

Intervention(s):

  • Drug: systemic chemotherapy
  • Other: laboratory biomarker analysis
  • Procedure: therapeutic surgical procedure
  • Radiation: radiation therapy

Phase:

N/A

Eligibility


DISEASE CHARACTERISTICS:

   - Meets 1 of the following criteria:

      - Histologically confirmed posterior fossa tumor

         - Newly diagnosed disease

         - Medulloblastoma OR non-medulloblastoma (pilocytic astrocytoma, ependymoma,
         atypical rhabdoid tumor, or others)

         - Scheduled to undergo craniotomy and tumor resection

      - Chiari malformation

         - Requires craniectomy for decompression

            - No secondary decompression

PATIENT CHARACTERISTICS:

   - No unexplained febrile illness

   - No active infection

   - No autoimmune disorders such as inflammatory bowel disease, juvenile rheumatoid
   arthritis, or systemic lupus erythematosus

   - No other immunosuppressive disorders (e.g., HIV infection)

PRIOR CONCURRENT THERAPY:

   - See Disease Characteristics

Ages Eligible for Study

4 Years - 21 Years

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Pediatric Hematology/Oncology
650-723-5535
Not Recruiting