Trial Search Results

Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer

This trial studies the chemotherapy toxicity on quality of life in older patients with stage I, stage II, stage III, or stage IV ovarian epithelial, primary peritoneal cavity, or fallopian tube cancer. Learning about the side effects of chemotherapy in older patients may help doctors plan better ways to treat cancer.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Gynecologic Oncology Group

Collaborator: National Cancer Institute (NCI)

Stanford Investigator(s):

Intervention(s):

  • Procedure: Assessment of Therapy Complications
  • Drug: Carboplatin
  • Biological: Filgrastim
  • Drug: Paclitaxel
  • Other: Pharmacological Study
  • Other: Quality-of-Life Assessment
  • Other: Questionnaire Administration

Phase:

N/A

Eligibility


Inclusion Criteria:

   - Eligible patients must have a histologically or cytologically confirmed diagnosis of
   adenocarcinoma of the ovary, peritoneum, or fallopian tube either by surgery, biopsy,
   fine-needle aspiration (FNA), paracentesis, or thoracentesis; a diagnosis of a
   mucinous cancer must be made by biopsy only

   - International Federation of Gynecology and Obstetrics (FIGO) stage I, II, III, and IV
   are eligible

   - Patients must have received no previous treatment for this malignancy other than
   surgery

   - Patients must be entered within eight weeks of confirmation of disease diagnosis by
   surgery, biopsy, FNA, paracentesis or thoracentesis if there is no primary surgery,
   and within twelve weeks of primary or staging surgery if patient received primary
   surgery

   - Absolute neutrophil count (ANC) greater than or equal to 1,500/mcl

   - Platelets greater than or equal to 100,000/mcl

   - Bilirubin less than or equal upper limit of normal (ULN)

   - Creatinine less than or equal to 1.5 x ULN

   - Patients must have a Gynecologic Oncology Group (GOG) performance status of 0, 1, 2 or
   3

   - Effective XX/XX/2014, only patients 75 years of age or older are eligible for
   enrollment; (04/23/2012) (08/12/2013)

   - Patients must have recovered from the effects of recent surgery

   - Patients must be free of active infection requiring antibiotics

   - Patients must have signed an approved informed consent and Health Insurance
   Portability and Accountability Act (HIPAA)

   - Patient and physician agree that they plan to conduct treatment according to Regimen 3

   - Patient can read and understand sufficient English to be able to respond to questions
   posed by the study instruments

Exclusion Criteria:

   - Patients who have received previous treatment for this malignancy other than surgery

   - Patients with other invasive malignancies whose previous cancer treatment
   contraindicates this protocol therapy

   - "Borderline tumors" (tumors of low malignant potential) by surgery or biopsy are
   excluded

   - Patients with medical conditions that in the opinion of the investigator render
   treatment on this protocol unsafe should be excluded

Ages Eligible for Study

75 Years - N/A

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
CCTO
650-498-7061
Not Recruiting