Trial Search Results

Multicenter Perioperative Opioid Pharmacogenetic Study

The purpose of this research study is to identify factors and genes (the DNA material that determines the makeup of the human body) that may be associated with how children respond to pain medication. Specifically, the investigators want to study factors that may be associated with pain sensitivity, morphine requirement after surgery and side-effects from morphine and other pain medications. The investigators expect that the information obtained in this research study will help us to develop more effective, safe, and tailored treatment options in the future.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Children's Hospital Medical Center, Cincinnati

Collaborator: Shanghai Children's Hospital

Stanford Investigator(s):




Inclusion Criteria:

   - children 6-17 years of age

   - ASA physical status 1 and 2

   - scheduled for tonsillectomy (T) and tonsillectomy and adenoidectomy (T and A)

   - Children with obstructive sleep apnea will also be included.

Exclusion Criteria:

   - children with developmental delay

   - liver and renal diseases,

   - preoperative pain requiring analgesics (e.g. chronic tonsillitis).

Ages Eligible for Study

6 Years - 17 Years

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
R J Ramamurthi
Not Recruiting