Pilot Study to Evaluate MR-guided Laser Ablation of Focal Lesions in Patients With Medically Refractory Partial Epilepsy

Inclusion Criteria:

   - Age 18 years or older at entry to protocol.

   - History of MRI lesional-related epilepsy for at least one year.

   - Failure to respond to more than 2 anti-epileptic drugs at adequate dose and duration.

   - Candidate for resective epilepsy surgery.

   - Considered healthy enough to undergo surgery with general anesthesia.

   - The patient has given written informed consent after the nature of the study and
   alternative treatment options have been explained.

   - Must have 3 months of seizure frequency recorded prior to procedure.

Exclusion Criteria:

   - Presence of any non-MRI compatible implanted electronic device.

   - Presence of a metallic prosthetic or implant including artificial hips, knees, joints,
   or rods and screws.

   - Active Major depression

   - History of Suicide attempts

   - History of Non-Epileptic Behavioral Spells