Phase I Pilot Study to Evaluate the Prognostic Value of Perfusion CT for Primary Cervical Cancer

Not Recruiting

Trial ID: NCT01805141

Purpose

The investigators hope to learn whether perfusion CT is a useful way to assess primary cervical tumor microenvironment and whether there is a relationship between pretreatment perfusion CT measurements and primary cervical tumor size, lymph node involvement (as assessed by standard of care pretreatment fludeoxyglucose Positron emission tomography/CT (FDG-PET/CT)), and treatment response (as assessed by standard of care 3-month post-therapy FDG-PET/CT).

Official Title

Phase I Pilot Study to Evaluate the Prognostic Value of Perfusion CT for Primary Cervical Cancer

Stanford Investigator(s)

Elizabeth Kidd
Elizabeth Kidd

Associate Professor of Radiation Oncology (Radiation Therapy)

Aya Kamaya, MD
Aya Kamaya, MD

Professor of Radiology (Body Imaging)

Andrei Iagaru
Andrei Iagaru

Professor of Radiology (Nuclear Medicine)

Eligibility


Inclusion criteria:

   - >18 years old

   - with biopsy-proven squamous, adenocarcinoma or adenosquamous cervical cancer

   - no history of prior pelvic radiation and should be able to receive chemoradiation

   - non-pregnant women who have not previously undergone a hysterectomy, as that would
   have removed the cervix.

   - able to give informed consent

Exclusion criteria:

   - Subjects whose tumors are not FDG avid on the pre-therapy PET.

   - Allergy or inability to receive iodinated CT contrast

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Melissa Usoz
650-723-8843

New Trial Alerts