Pivotal Response Treatment Package for Young Children With Autism

Inclusion Criteria:

   - Diagnosis of Autism Spectrum Disorder (ASD) based on Autism Diagnostic Interview-
   Revised (ADI-R), Autism Diagnostic Observation Schedule (ADOS-2), and expert clinical
   opinion

   - Males and females in good medical health between 2.0 and 5.11 years

   - Ability to participate in the testing procedures to the extent that valid standard
   scores can be obtained

   - Language delay as measured by the Preschool Language Scale: Standard score at least 1
   Standard Deviation below average for expressive language ability

   - Stable treatment, speech therapy, school placement, psychotropic medication(s) or
   biomedical intervention(s) for at least 1 month prior to baseline measurements with no
   anticipated changes during study participation

   - No more than 60 minutes of individual 1:1 speech therapy per week

   - Availability of at least one parent who can consistently participate in parent
   training and research measures

   - Parents intend on continuing Pivotal Response Treatment Package (PRT-P) for a minimum
   of 12 weeks

   - Parents must be 18 years of age or older

Exclusion Criteria:

   - Current or lifetime diagnosis of severe psychiatric disorder, such as bipolar disorder

   - Receiving in-home Applied Behavior Analysis (ABA) of 10 hours or more

   - A genetic abnormality, such as Fragile X

   - Presence of active medical problem, such as unstable seizure disorder or heart disease

   - Previous adequate PRT trial

   - Participants living more than 50 miles from Stanford University

   - At least one room of the house must be available to be dedicated to treatment during
   session times

   - There must be no serious health and safety risks present in the home environment

   - The research team has the right to refuse to perform sessions in-home even if the
   criteria above are met