Trial Search Results

Epidemiologic Study of Hepatocellular Carcinoma in the US

The purpose of this study is:

- to investigate the risk factors of HCC among Americans with focus on lifestyle factors and energy balance.

- to identify single nucleotide polymorphisms (SNPs) and haplotypes that are associated with HCC risk through a genome-wide search.

- to assess if genetic susceptibility differs by hepatitis virus infection or lifestyle factors, and to explore if there are interplays or effect modifications between genetic factors and viral infection or lifestyle factors.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University

Stanford Investigator(s):

Eligibility


Inclusion Criteria for HCC cases:

   - a diagnosis of primary liver cancer (excluding secondary tumors)

   - a diagnosis of hepatocellular carcinoma if histology is available (excluding those
   diagnosed in intrahepatic bile duct, bile canals, biliary passages, canaliculi, gall
   duct and gallbladder)

   - a diagnosis of hepatocellular carcinoma with or without microscopic evaluation
   (including those diagnosed with clinical evidence, lab tests and direct visualization
   or radiographic and other imaging evidence)

   - a histology of primary hepatocellular carcinoma when the patients had a prior
   diagnosis of other forms of cancer (excluding those who had no histological diagnosis
   of hepatocellular carcinoma while having a prior history of other cancer;

   - age at diagnosis between 35 and 84 years

   - living in Connecticut, New Jersey, New York, or Hawaii for at least a year as regular
   residents.

Exclusion Criteria for HCC cases:

   - uncertain diagnoses or classification of malignancy, such as unknown origin

   - a diagnosis of primary tumors in other organs, not in the liver

   - unable to communicate well enough in English or Spanish

   - having medical conditions, such as mental disorders, that prevent the subject from
   providing reasonably comprehensible information or from being able to give informed
   consent.

   - diagnosed at age <35 years or >84 years

   - temporary residents of New Jersey, Connecticut, New York, or Hawaii

Inclusion Criteria for control subjects:

   - age between 35 and 84 years

   - living in New Jersey or Connecticut for at least a year as regular residents

   - able to communicate well in English or Spanish

   - having no medical conditions, such as mental disorders, that prevent them from
   providing adequately comprehensible information

   - potential subjects with a previous history of cancer are eligible.

Exclusion Criteria for control subjects:

   - age < 35 years or > 84 years

   - temporary residents of New Jersey or Connecticut

   - unable to speak English or Spanish

   - cannot provide adequately comprehensible information

Ages Eligible for Study

35 Years - 84 Years

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Pauline Nguyen
Recruiting