Trial Search Results

Study of Refeeding to Optimize iNpatient Gains

The purpose of this study is to compare the efficacy, safety, and cost-effectiveness of lower calorie refeeding versus higher calorie refeeding in hospitalized adolescents with anorexia nervosa.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

University of California, San Francisco

Collaborator: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Stanford Investigator(s):


  • Other: Higher Calorie Refeeding
  • Other: Lower Calorie Refeeding




Inclusion Criteria:

   - diagnosis of AN

   - atypical AN

   - no hospital admissions for the previous six months

   - meet hospitalization criteria: daytime heart rate (HR) < 50 bpm or night time HR < 45
   bpm, blood pressure (BP) <90/45 mmHg, temperature < 35.6° C, or symptomatic
   orthostasis defined by increase in HR > 35 bpm or decrease in systolic BP > 20 mmHg or
   decrease in diastolic BP > 10 mmHg from lying to standing

Exclusion Criteria:

   - diagnosis of bulimia nervosa [DSM-5]

   - currently in remission (as defined by weight and EDE-Q score)

   - admission for food refusal without malnutrition

   - current pregnancy

   - chronic disease (e.g. immune/endocrine disorders, pulmonary, cardiac, or renal

   - current suicidality or psychosis

   - < 60% mBMI

Ages Eligible for Study

12 Years - 24 Years

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Not Recruiting