Trial Search Results
Refeeding Syndrome in Anorexia Nervosa
The purpose of this multi-center randomized controlled trial is to compare lower calorie refeeding to higher calorie refeeding for hospitalized adolescents and young adults with AN. The investigators will compare efficacy (achievement and maintenance of clinical remission at 12 months), safety during hospitalization, and cost effectiveness (including costs of initial and re hospitalization, 12 month follow up and safety/adverse events).
Stanford is currently accepting patients for this trial.
Collaborator: National Institutes of Health (NIH)
- Behavioral: High calorie refeeding
- Behavioral: Low calorie refeeding
- Adolescents hospitalized for medical instability secondary to malnutrition will be
eligible as follows.
1. diagnosis of AN, atypical AN
2. age 12-24 years
3. no hospital admissions for the previous six months
4. meet hospitalization criteria (daytime HR < 50 bpm or night time HR < 45 bpm, BP
<90/45 mmHg, temperature < 36? C or orthostasis defined by increase in HR > 20 bpm or
decrease in systolic BP > 20 mmHg or decrease in diastolic BP > 10 mmHg from lying to
1. diagnosis of bulimia nervosa [DSM-5]
2. current pregnancy
3. admission for food refusal without malnutrition
4. chronic disease (e.g. immune/endocrine disorders,pulmonary, cardiac, or renal disease)
5. current suicidality or psychosis.
Ages Eligible for Study
12 Years - 24 Years
Genders Eligible for Study