©2022 Stanford Medicine
Web-Delivered Acceptance & Commitment Therapy for Smokers With Bipolar Disorder
Not Recruiting
Trial ID: NCT02750904
Purpose
This purpose of the study is to develop and test a new website to help people who have
bipolar disorder quit smoking.
Official Title
Web-Delivered Acceptance & Commitment Therapy for Smokers With Bipolar Disorder
Stanford Investigator(s)
Eligibility
Inclusion Criteria:
1. Age 18 or older
2. Daily smoker for the past year, averaging at least 5 cigarettes per day for the past
30 days, with expired-air carbon monoxide (CO) level ≥ 4 ppm
3. Motivated to quit smoking (i.e., endorse plans to quit in the next 30 days at the time
of phone pre-screening)
4. Meets lifetime criteria for bipolar I or II disorder, based on DSM-V criteria
5. Willing to be randomly assigned to either treatment group
6. Has at least weekly access to a high-speed Internet connection via a tablet, laptop or
desktop computer
7. Willing and able to read in English
8. Is under care of a clinician for the treatment of bipolar disorder
9. Willing to authorize communication with the clinician regarding study participation
and clinical deterioration
10. Willing to use the nicotine patch to help quit smoking
Exclusion Criteria:
1. Participating in other smoking cessation interventions
2. Currently using any pharmacotherapies for smoking cessation
3. Previous use of the Smokefree.gov website
4. Meets DSM-V criteria for current mania
5. Meets DSM-V criteria for a current major depressive episode and symptoms are currently
severe (Patient Health Questionnaire-9 score > 14)
6. Current psychotic symptoms
7. Psychiatric hospitalization within one month prior to enrollment
8. Current suicidal or homicidal ideation
9. Meets criteria for a DSM-V diagnosis of a moderate or severe substance use disorder in
past month prior to enrollment
10. Unstable medical condition
11. Any medical or psychiatric condition that, in the opinion of the investigator, is
severe enough to interfere with protocol adherence or ability to benefit from the
intervention
12. Any medical conditions that would preclude use of the nicotine patch (e.g., recent
myocardial infarction, significant skin disorder, previous severe adverse reaction to
nicotine patch, pregnant or breast feeding, assessed with our standard protocol for
determining NRT eligibility)
13. Employee or family member of the investigator or study center, or member of the same
household as another research participant
Intervention(s):
behavioral: Experimental plus Nicotine Replacement Therapy
behavioral: Control plus Nicotine Replacement Therapy
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Michael Ostacher
650-849-0494