Trial Search Results

The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)

The purpose of this study is to assess whether the type of anesthesia, narcotic-based versus inhalational anesthesia administered during cardiopulmonary bypass (CPB) surgery contributes to the wide variation in neurologic recovery and developmental outcome after surgery in infants with congenital heart disease.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University

Collaborator: The Gerber Foundation

Stanford Investigator(s):

Intervention(s):

  • Drug: Isoflurane
  • Drug: Fentanyl
  • Drug: Dexmedetomidine
  • Device: Electroencephalogram
  • Behavioral: Bayley III

Phase:

N/A

Eligibility


Inclusion Criteria:

   - Neonates of at least 32 weeks of gestation, infants and children up to 2 years of age
   admitted to The Children's Hospital for treatment of cyanotic or non-cyanotic heart
   disease requiring surgical intervention.

   - Admitting diagnosis of cyanotic or non-cyanotic heart disease

Exclusion Criteria:

   - Neonates less than 32 weeks of gestational age, and children more than 2 years of age.

   - Any documented central nervous system malformations.

   - Any potential subject requiring unexpected postoperative Extracorporeal membrane
   oxygenation (ECMO) support

Ages Eligible for Study

N/A - 24 Months

Genders Eligible for Study

All

Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Not Recruiting