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Comparing Diuretic Strategies in Hospitalized Heart Failure
Not Recruiting
Trial ID: NCT03999216
Purpose
We will conduct a pragmatic randomized trial comparing whether using a combination of two
types of diuretics (loop + thiazide) compared with using a single diuretic (loop only) will
result in shorter hospital stays for patients hospitalized with heart failure.
Official Title
Creating a Platform for Point-of-Care Pragmatic Clinical Trials: Comparing Diuretic Strategies in Heart Failure
Stanford Investigator(s)
Tara I. Chang
Stanford University Professor of Nephrology
Eligibility
Inclusion Criteria:
Any adult (age ≥18 years) admitted to the Heart Failure Service at Stanford Health Care
with an indication for treatment with a diuretic.
Exclusion Criteria:
1. admission to the intensive care unit or cardiac care units
2. maintenance dialysis on admission
3. any mechanical circulatory support on admission
4. history of heart transplant
5. allergy / intolerance to loop or thiazide diuretics
6. admission serum sodium < 125 meq/L (from EPIC)
7. admission serum potassium < 3.0 meq/L (from EPIC)
Intervention(s):
drug: Loop Diuretics vs. loop + thiazide diuretics
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Tara Chang, MD, MS