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Characterization of Treatment Responses in Lymphedema
Not Recruiting
Trial ID: NCT03783715
Purpose
This study is designed to investigate the treatment response of lymphedema, of the upper or
lower extremity, during clinical, pharmacologic treatment of lymphedema with oral ketoprofen.
Correlation of clinical responses (changes in limb volume and skin thickness) with changes in
the inflammasome will help to define the molecular substrate of treatment response.
Official Title
Characterization of Treatment Responses in Lymphedema
Stanford Investigator(s)
Stanley G. Rockson, MD
Allan and Tina Neill Professor of Lymphatic Research and Medicine
Eligibility
Inclusion Criteria:
- Participants with a history of acquired lymphedema
- Stage 1, 2, or 3
- 18-75 years
- Clinical use of ketoprofen for lymphedema
Exclusion Criteria:
- Active cancer, infection, bleeding tendency, inflammatory disease and/or taking
anti-inflammatory or anti-leukotriene medication will be excluded.
- Pregnant or lactating females
- Inability to take ketoprofen (contra-indicated, e.g patients with known CV, GI, renal,
hepatic disease).
- Other severe acute or chronic medical or psychiatric condition or laboratory
abnormality that may increase the risk associated with study participation, may
interfere with interpretation of study results, and in the judgement of the
investigator, would make the participation inappropriate for entry into this study.
Intervention(s):
drug: Ketoprofen
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Leslie Roche, RN
650-723-1396