Trial Search Results

A Human In-vivo Model for the Detection of Inflammatory and Nociceptive Biomarkers

This study aims to establish a novel approach assisting the rational development of analgesic and anti-inflammatory drugs. In a first step we will test in healthy human volunteers whether proteins mediating inflammation and pain can be detected in an experimentally induced inflammatory skin lesion. Fluids that will be used to detect such proteins will be collected from the inflamed skin site via small porous catheters. We wish to establish the expression pattern of different proteins and correlate it with various tests assessing pain.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Martin Angst

Stanford Investigator(s):


  • Procedure: Micro-plasmapheresis




Inclusion Criteria:1. Age between 21-60. 2. Skin type II or III according to the
classification of Fitzpatrick (II: fair skin, always burns, sometimes tans, III: medium
skin, sometimes burns, always tans). Exclusion Criteria:1. History of a significant
systemic disease, a dermatological disease, bleeding disorder, or chronic pain.

2. Consumption of analgesic drugs. 3. Hypersensitivity to sunlight.

Ages Eligible for Study

21 Years - 60 Years

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Martin Angst
Not Recruiting