Trial Search Results

Effects of Epidural Lidocaine on the Pharmacokinetic and Pharmacodynamic Profiles of DepoDurĀ® After Cesarean Delivery

To evaluate the levels of morphine in a patient's blood when morphine is given into the epidural space in the form of DepoDurĀ® either alone or following a dose of lidocaine also given in the epidural space.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University

Stanford Investigator(s):


  • Drug: DepoDur following epidural lidocaine
  • Drug: DepoDur following spinal anesthetic




Inclusion Criteria:

Inclusion criteria will include healthy parturients between the ages of 18 and 40 who have
American Society of Anesthesiologists physical status I or II, have an uncomplicated,
singleton, term pregnancy, and are scheduled to undergo cesarean delivery.

Exclusion Criteria:

Exclusion criteria for the study will included refusal to participate, American Society of
Anesthesiologists physical status III or higher or any severe uncontrolled medical
condition, significant systemic medical or obstetric disease, morbid obesity, opioid,
Nonsteroidal Antiinflammatory Drug (NSAID), or local anesthetic allergy or intolerance,
chronic analgesic or antidepressant use, accidental dural puncture, ineffective spinal or
epidural, and conversion to general anesthesia.

Ages Eligible for Study

18 Years - 40 Years

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Brendan Carvalho