Trial Search Results

DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem Glioma

The main goal of this study is to analyze in details the genetic make-up of tumors in patients with diffusebrainstem glioma and similar brainstem tumors. We hope that the results of this study will help us developnew and better treatments for patients with these types of tumors, that our results may help choose the righttreatment for each patient, and that we will be able to predict which patients are more likely or not torespond to a certain type of treatment.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

St. Jude Children's Research Hospital

Stanford Investigator(s):


Inclusion Criteria

   - Patients of any age with clinical and radiologic diagnosis of diffuse brainstem glioma

   - Patients with other high-grade gliomas originating in the brainstem

   - Patients with focal gliomas (WHO grade I/II) of the brainstem

   - Enrollment in the current version of the St. Jude Tissue Bank protocol for patients
   whose tissue samples were obtained at diagnosis and who received treatment at St. Jude
   Children's Research Hospital (SJCRH), or correspondent tissue banking consent for
   patients treated in other institutions if tissue was obtained prior to death (as
   applicable, depending on the standard of each institution)

Exclusion Criteria

   - Patients with any type of infiltrative low-grade (WHO grade II) or high-grade glioma
   (WHO grade III and IV) originating outside the brainstem

   - Patients harboring primary brainstem tumors with other histologic diagnoses (e.g.,

Ages Eligible for Study

N/A - 18 Years

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Michelle Monje
Not Recruiting