Trial Search Results

Specialized Radiation Therapy in Treating Patients With Stage II, Stage III, Stage IV, or Recurrent Non-Small Cell Lung Cancer and Poor Performance Status

RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue.

PURPOSE: This phase I trial is studying the side effects and best dose of specialized radiation therapy in treating patients with stage II, stage III, stage IV, or recurrent non-small cell lung cancer and poor performance status.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

University of Texas Southwestern Medical Center

Collaborator: National Cancer Institute (NCI)

Stanford Investigator(s):


  • Radiation: hypofractionated radiation therapy


Phase 1



   - Histologically or cytologically confirmed non-small cell lung cancer

      - Stage II-IV and/or recurrent disease

      - No small cell histology

   - Measurable or evaluable disease

      - Tumor not amenable to surgical resection

      - Tumor not eligible for stereotactic body radiation therapy

   - No prior radiotherapy to the region of the study cancer that would result in overlap
   of radiation therapy fields


   - Zubrod performance status 2-4

   - Not pregnant or nursing

   - Negative pregnancy test

   - Fertile patients must agree to use effective contraception

   - Must complete all required pretreatment evaluations


   - See Disease Characteristics

   - More than 1 week since prior chemotherapy or chemoradiation therapy

   - No concurrent chemotherapy

   - No other concurrent antineoplastic therapy (including standard-fractionated
   radiotherapy to the chest, chemotherapy, biological therapy, vaccine therapy, and
   surgery) 1 week before, during, and for 1 week after completion of study therapy

Ages Eligible for Study

18 Years - 120 Years

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Cancer Clinical Trials Office
Not Recruiting