Trial Search Results

4D-CT-based Ventilation Imaging for Adaptive Functional Guidance in Radiotherapy

To develop and investigate a novel radiotherapy technique for preserving lung function based on a map of lung function.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Billy W. Loo Jr.


  • Device: Real-time Position Management system
  • Device: Discovery ST multislice PET/CT scanner
  • Device: Infinia Hawkeye SPECT/CT gamma camera
  • Device: Pinnacle3 treatment planning system
  • Device: SKYLight nuclear camera
  • Drug: DTPA


Early Phase 1


Inclusion Criteria:

   - Eligible disease(s)/stage(s) AJCC Stage I, II, III or IV lung cancer of any histology
   to be treated using radiotherapy will be eligible for this study. Note that we will
   carefully consider the inclusion of cases with turbulent flow or greater flow
   velocities (Cabahug et al., 1996; Crawford et al., 1990) and COPD cases (Magnant et
   al., 2006) due to the impaction of aerosol particles in central airways.

   - Allowable type and amount of prior therapy. Any types and amounts of prior therapy
   will be allowed for this study.

   - Age restriction and/or gender/ethnic restrictions

   - Patients must be greater than or equal to 18 years of age.

   - There are no gender or ethnic restrictions.

   - Life expectancy restrictions - None.

   - ECOG or Karnofsky Performance Status

   - Not employed. Note that patients will need to be sufficiently healthy to undergo
   audiovisual (AV) biofeedback to generate high quality 4D-CT images.

   - Requirements for organ and marrow function None.

   - Ability to understand and the willingness to sign a written informed consent document.

Exclusion Criteria:

Children (less than 18 years of age), pregnant women, Stanford employees or students, or
prisoners will be excluded from this study.

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Cancer Clinical Trials Office
Not Recruiting