Subtotal Resection of Large Acoustic Neuromas With Possible Stereotactic Radiation Therapy

Not Recruiting

Trial ID: NCT01129687

Purpose

The investigators study is to investigate safety and efficacy of performing a planned incomplete removal of large acoustic neuroma tumors to decrease surgical morbidity and yet avoid tumor recurrence by post-operative radiation therapy.

Official Title

Multicenter Prospective Analysis of Treatment Outcome in Patients With Large Acoustic Neuromas

Eligibility


Inclusion Criteria:

   - Adult patients with acoustic neuromas the widest diameter of 2.5 cm or larger at the
   cerebellopontine angle are eligible for this trial.

   - Patients that are deemed good surgical candidates based on age, general health,
   genetic predispositions, and hearing in contralateral side would be included as the
   subjects of this trial.

   - Although we would include patients with neurofibromatosis II in this trial,
   considering their genetic predisposition for recurrence, we would analyze their
   outcome as a separate group.

Exclusion Criteria:

   - Patients who have received any form of treatment of their acoustic neuromas prior to
   enrollment in the study including surgery or radiation therapy.

Intervention(s):

procedure: Microsurgery

procedure: Stereotactic radiation therapy

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
ashkan monfared, MD
202-741-3250