Trial Search Results
Aminophylline to Prevent Acute Kidney Injury in Children After Cardiac Surgery
Children with congenital heart defects often need cardiac surgery with cardiopulmonary bypass (the "heart-lung machine"). Approximately 35 to 50% of these children will have "acute kidney injury," or damage to the kidneys, after the procedure. We currently have few medications to prevent this kidney injury. The hypothesis of this study is that giving aminophylline after heart surgery can decrease the acute kidney injury.
Stanford is currently not accepting patients for this trial.
- Drug: Aminophylline
- Drug: Placebo
- Less than 18 years old, undergoing cardiac surgery with bypass
- neonates must be at least 36 weeks gestational age
- History of arrythmia or seizure, on extracorporeal membrane oxygenation (ECMO)
support, already taking aminophylline/theophylline, liver failure, sepsis, on renal
Ages Eligible for Study
N/A - 18 Years
Genders Eligible for Study