Trial Search Results

Personal Genomics for Preventive Cardiology

The purpose of this study is to see if providing information to a person on their inherited (genetic) risk of cardiovascular disease (CVD) helps to motivate that person to change their diet, lifestyle or medication regimen to alter their risk.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University


  • Behavioral: genetic risk score for coronary risk factors




Inclusion Criteria:

   - Adults age > 18

   - Patient seeking cardiovascular risk evaluation

   - At intermediate (6-20%) or high risk (> 20%) over 10 years of CAD as defined by
   Framingham 10 year risk score AND/OR at > 20% risk of CAD over 30 years using the
   Framingham 30 year risk calculator

   - The genetic risk factors have been evaluated predominantly in white/European subjects.
   However, there is considerable overlap in the genetic architecture of South Asians and
   Hispanic/Latino populations. Therefore, we will limit our initial studies to these
   three race/ethnicity groups.

Exclusion Criteria:

   - History of myocardial infarction, angina, stroke, peripheral arterial disease, PCI, or

   - Already on lipid lowering therapy

   - Anticipated survival <1 year (e.g. metastatic cancer)

   - Serious conditions that would limit ability to adhere to recommendations (inability to
   take statins, exercise)

   - Already had genetic testing

   - Concurrent enrollment in another clinical trial

   - Pregnant or breastfeeding

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Josh Knowles
Not Recruiting