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National Eye Institute Biorepository for Retinal Diseases
Recruiting
Trial ID: NCT01496625
Purpose
Background:
- To understand diseases of the retina and the eye, information is needed about people with
and without such diseases. Researchers want to study these people and follow them over time.
They also want to study body tissues and blood to understand the nature of eye disease.
Studying genes, cells, and tissues may help them understand why some people get eye problems
and others do not, or why some people respond to treatment while others do not. Researchers
want to collect physical samples and personal data to develop a National Eye Institute
database.
Objectives:
- To collect health information and blood and tissue samples from people with and without eye
diseases, to be used in research studies.
Eligibility:
- Individuals of any age with different types of eye disease.
- Healthy volunteers with no history of eye disease.
Design:
- Participants may be recruited from National Eye Institute studies or may be referred
from other sources.
- Participants will be screened with a physical exam and medical history. They will also
have a full eye exam. Questions will be asked about family medical history, especially
about eye disease.
- Blood samples will be collected. Other samples, such as saliva, tears, hair, stool, and
urine, may be collected as needed. Adult participants may also provide a skin sample.
- Tissue or fluid from eye collected as part of eye care or treatment may also be added to
the database.
- No treatment will be provided as part of this study.
Official Title
NEI Intramural Biorepository for Retinal Diseases
Stanford Investigator(s)
Eligibility
- INCLUSION CRITERIA:
Participants will be eligible if they:
- Have the ability to understand and sign an informed consent or have a parent/legal
guardian to do so if they are minor children.
- Manifest diagnosed or undiagnosed retinal disease(s), or could serve as an unaffected
control suitable for comparison to participants with various retinal diseases,
particularly AMD and diabetic retinopathy (taking into account matching factors such
as age and past ocular history).
EXCLUSION CRITERIA:
Participants will not be eligible if they:
- Are unable or unwilling to give informed consent that includes collection and study of
at least one peripheral blood sample.
- Are unable or unwilling to give informed consent that includes use of NIH medical
records and clinical samples for research.
- Have a systemic disease that compromises the ability to provide adequate
ophthalmologic examination or treatment.
Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305