Trial Search Results

Study of Brentuximab Vedotin Combined With Bendamustine in Patients With Hodgkin Lymphoma

The purpose of this research study is to obtain information on the effectiveness and safety of a drug called brentuximab vedotin when given in combination with another drug called bendamustine. The study will consist of a Phase 1 (safety) cohort followed by a Phase 2 (expansion) cohort.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Seagen Inc.


  • Drug: brentuximab vedotin
  • Drug: bendamustine


Phase 1/Phase 2


Inclusion Criteria:

   - Histopathological diagnosis of classical Hodgkin lymphoma

   - Failed standard front-line therapy

   - Measurable disease of at least 1.5 cm as documented by radiographic technique

   - Eastern Cooperative Oncology Group performance status less than or equal to 2

Exclusion Criteria:

   - Received prior salvage therapy, including radiotherapy

   - Chemotherapy, radiotherapy, biologics, and/or other treatment with immunotherapy not
   completed 4 weeks prior to first dose of study drug

   - Concurrent use of other investigational agents

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Not Recruiting