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Optimization of Time-of-Flight Mass Cytometry (CyTOF) Analysis for Evaluation of Immune Changes Following Surgery
Not Recruiting
Trial ID: NCT01882569
Purpose
Surgical trauma triggers a massive inflammatory response. Over time, both the innate and
adaptive branches of the immune system are affected by surgical trauma. The purpose of this
study is to use a single cell flow cytometry approach to characterize the cellular and
molecular mechanisms involved in the inflammatory response to surgical trauma.
Official Title
Detection of Immune Changes as a Result of Surgical Trauma in Human Back Surgery Subjects: Optimization of CyTOF Analysis
Stanford Investigator(s)
Martin S. Angst
Professor of Anesthesiology, Perioperative and Pain Medicine
Eligibility
Inclusion Criteria:
1. Ages 18 - 90
2. Men and women
3. Undergo back surgery
Exclusion Criteria:
1. Any systemic disease that might compromise the immune system (e.g. lupus)
2. Current diagnosis of cancer
3. Any condition that, in the opinion of the investigator, might compromise the integrity
of the study or safety of the participant.
4. Unwilling to sign informed consent
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305