Trial Search Results

Increasing the Removal of Protein-Bound Solutes During Extended Hours Hemodialysis

Hemodialysis keeps patients with renal failure alive but does not restore normal health. Retention of chemicals that bind to plasma proteins and are therefore poorly removed by dialysis may contribute to ill health in patients receiving conventional treatment. This proposal will test the effect of a new method designed to improve the removal of protein-bound solutes during dialysis. The effects on blood chemical levels of two different dialysis prescriptions will be tested in patients already undergoing nocturnal in-center hemodialysis three times weekly.

Stanford is currently accepting patients for this trial.

Lead Sponsor:

Palo Alto Veterans Institute for Research

Stanford Investigator(s):


  • Other: low dialysate flow, smaller dialyzer
  • Other: high dialysate flow, larger dialyzer




Inclusion Criteria:

   - stable on nocturnal in-center dialysis located close to Stanford University and VA
   Palo Alto

Exclusion Criteria:

   - recent use of antibiotics

   - gastrointestinal disease

Ages Eligible for Study

18 Years - 85 Years

Genders Eligible for Study


Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Timothy Meyer, MD