A Study of Vismodegib With Surgery in Participants With Previously Untreated Basal Cell Carcinoma

Inclusion Criteria:

   - Diagnosis of non-infected, not recurrent, previously untreated basal cell carcinoma

   - Free of any significant physical abnormalities (e.g., tattoos) at the target basal
   cell carcinoma site

   - Willing and able to participate in the study as an outpatient and agreement to make
   frequent visits to the clinic during the treatment and follow-up periods and to comply
   with study requirements

Exclusion Criteria:

   - Prior treatment with vismodegib

   - Known hypersensitivity to any of the study drug excipients

   - Any metastatic basal cell carcinoma

   - Any locally advanced basal cell carcinoma considered to be inoperable or to have a
   medical contraindication to surgery

   - Evidence of clinically significant and unstable diseases or conditions (e.g.,
   cardiovascular, immunosuppressive, hematologic)

   - Any dermatological disease at the target basal cell carcinoma site that may cause
   difficulty with examination

   - Recent, current, or planned participation in another experimental drug study