Trial Search Results

Study of an Electronic Health Record-embedded Severe Sepsis Early Warning Alert

The investigators hypothesize that implementing an electronic health record-based early warning system for severe infections (severe sepsis) will decrease the time to antibiotic order. The study will consist of an algorithm which will monitor lab values, vital signs, and nursing documentation for signs of severe sepsis. When these criteria are met, an alert will be delivered via the electronic health record to a nurse and doctor and simultaneously an alert via pager to another nurse. The investigators plan to randomize which patients will generate these alerts and analyze the data after collecting information for approximately 6 months which will be sufficient to detect a 10% difference in the two patient groups.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University

Stanford Investigator(s):


  • Behavioral: Severe sepsis early warning best practice alert
  • Behavioral: Standard care




Inclusion Criteria:

   - Admitted to Stanford Hospital (inpatient or observation status) to any medical or
   surgical service for at least 24 hours during the period of the study

Exclusion Criteria:

   - Admitted to an intensive-care level service (MICU, SICU, CVICU, CCU)

   - Patient code status is DNR/C (comfort care only)

   - Patients less than 18 years of age at time of admission.

   - Emergency Department patients (may be included in the near future)

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Not Recruiting