Role of GLP-1 in Hyperinsulinemic Hypoglycemia Post-bariatric Surgery

Inclusion Criteria:

   - Men and women ages 18-65

   - BMI 25-40 with a clinical diagnosis of severe symptomatic hypoglycemia after bariatric
   surgery

Exclusion Criteria:

   - Acute medical illness, such as acute bacterial or viral syndrome, febrile illness,
   acute abdominal symptoms, orthopedic injury within one week

   - History of cardiac failure, renal insufficiency (estimated Crcl<30cc/min), hepatic
   insufficiency, chronic obstructive pulmonary disease, anemia (Hct<30%), or
   uncontrolled hypertension (SBP>160 or DBP>100)

   - Pregnancy

   - Use of medications that affect glucose metabolism

   - Fasting glucose >150 or HbA1c>7.5 on Metformin

   - Women of childbearing potential (will have a pregnancy test, in addition use of
   abstinence for at least one month prior to study or use two types of contraceptives,
   hormonal implant or Depo Provera)

   - Active, uncontrolled psychiatric disease

   - Participating in other studies or have received investigational medications within the
   past month or 5 half-lives of the drug, whichever is longer.