Trial Search Results
Non-Damaging Photothermal Therapy of Non-exudative Age Related Macular Degeneration
This is a randomized controlled study of non-damaging photothermal macular grid laser versus sham laser therapy in patients with dry age-related macular degeneration (AMD) and large high-risk drusen. The goal of the study is to determine if this treatment will reduce macular drusen volume and also whether this might improve visual acuity or reduce the risk of conversion to advanced age-related macular degeneration defined as development of choroidal neovascularization or geographic atrophy.
Stanford is currently not accepting patients for this trial.
Collaborator: Bascom Palmer Eye Institute
- Device: macular laser treatment
- Device: sham macular laser treatment
1. Older than 60 years of age.
2. Male or female patients with nonexudative AMD with a drusen volume of of at least
0.03mm3 in the central 3mm circle
3. Adequate pupil dilatation and clear media to perform colour, red-free imaging and
fundus fluorescein angiography, fundus autofluorescence imaging and OCT.
4. Able to give an informed consent.
1. Presence of signs of advanced AMD, such as CNV, haemorrhages or macular atrophy based
on OCT and fundus autofluorescence photography (FAF).
2. Previous macular laser treatment.
3. Any previous ocular condition that may be associated with a risk of developing macular
4. Vitreomacular traction determined clinically and /or by OCT, which in the opinion of
the investigator, contributes to the macular oedema (associated or causing a
detachment of the fovea).
5. Presence of other macular disease such as epiretinal membrane, macular telangiectasia.
6. Important known allergies to sodium fluorescein dye used in angiography.
7. Ocular or periocular infections.
8. Planned intra-ocular surgery within one year.
9. Patient is unavailable for follow-up visits.
Ages Eligible for Study
60 Years - N/A
Genders Eligible for Study