Web-Delivered Acceptance & Commitment Therapy for Smokers With Bipolar Disorder

Inclusion Criteria:

   1. Age 18 or older

   2. Daily smoker for the past year, averaging at least 5 cigarettes per day for the past
   30 days, with expired-air carbon monoxide (CO) level ≥ 4 ppm

   3. Motivated to quit smoking (i.e., endorse plans to quit in the next 30 days at the time
   of phone pre-screening)

   4. Meets lifetime criteria for bipolar I or II disorder, based on DSM-V criteria

   5. Willing to be randomly assigned to either treatment group

   6. Has at least weekly access to a high-speed Internet connection via a tablet, laptop or
   desktop computer

   7. Willing and able to read in English

   8. Is under care of a clinician for the treatment of bipolar disorder

   9. Willing to authorize communication with the clinician regarding study participation
   and clinical deterioration

10. Willing to use the nicotine patch to help quit smoking

Exclusion Criteria:

   1. Participating in other smoking cessation interventions

   2. Currently using any pharmacotherapies for smoking cessation

   3. Previous use of the Smokefree.gov website

   4. Meets DSM-V criteria for current mania

   5. Meets DSM-V criteria for a current major depressive episode and symptoms are currently
   severe (Patient Health Questionnaire-9 score > 14)

   6. Current psychotic symptoms

   7. Psychiatric hospitalization within one month prior to enrollment

   8. Current suicidal or homicidal ideation

   9. Meets criteria for a DSM-V diagnosis of a moderate or severe substance use disorder in
   past month prior to enrollment

10. Unstable medical condition

11. Any medical or psychiatric condition that, in the opinion of the investigator, is
   severe enough to interfere with protocol adherence or ability to benefit from the
   intervention

12. Any medical conditions that would preclude use of the nicotine patch (e.g., recent
   myocardial infarction, significant skin disorder, previous severe adverse reaction to
   nicotine patch, pregnant or breast feeding, assessed with our standard protocol for
   determining NRT eligibility)

13. Employee or family member of the investigator or study center, or member of the same
   household as another research participant