Gastric Acid Suppression and Probiotic Colonization

Not Recruiting

Trial ID: NCT03327051

Age - 18 Years-75 Years Gender - All Accepting Healthy Volunteers - yes

Purpose

Probiotics are over-the-counter dietary products with microorganisms that are generally consumed for health benefit. However, the durability of these microorganisms is unclear, particularly when they pass through the highly acidic environment of the stomach. We will test the colonization of these microorganisms among individuals who consume probiotics with and without acid suppression therapy.

Official Title

The Effect of Gastric Acid Suppression on Probiotic Colonization

Eligibility


Inclusion Criteria:

   - Healthy volunteers ages 18 years and ≤ 75 years.

   - Able to visit the study Doctor's office 3 times, answer 3 questionnaires, and provide
   stools and blood samples.

Exclusion Criteria:

   - Gastric cancer, Barrett's esophagus cancer, any gastrointestinal condition, or soy or
   gluten sensitivity

   - Previous abdominal surgery

   - Currently pregnant or nursing

   - Had H. Pylori Infection

   - Diagnosed with any chronic medical condition other than hypertension or hyperlipidemia

   - Currently consuming herbs or probiotics

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Intervention(s):

drug: Omeprazole

dietary supplement: VSL #3

drug: Placebo

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Berkeley Limketkai
650-736-0431

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