Trial Search Results

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures

THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia. The use of high-flow nasal cannula oxygen supplementation during anesthesia for surgical procedures has been a recent development in the adult population, with limited data analyzing the pediatric population. This study will determine whether high flow nasal cannula oxygen supplementation during surgical or endoscopic procedures can safely prevent desaturation events in children under anesthesia.

Stanford is currently not accepting patients for this trial.

Lead Sponsor:

Stanford University


  • Device: High-flow nasal cannula




Inclusion Criteria:

   - Pediatric patients less than or equal to 18 years old undergoing general anesthesia
   for procedures or surgeries at Lucile Packard Children's Hospital.

Exclusion Criteria:

   - Pregnancy, absence of parent or legal guardian able to provide written consent for
   study participation, anatomical or surgical contraindications (epistaxis, basilar
   skull fractures or abnormalities, nasal surgery or obstruction, nasal fractures, nasal
   vascular abnormalities), papillomatosis, tracheostomy, emergent surgery for which
   application of HFNC might delay surgery or might result in increased aspiration risk.

Ages Eligible for Study

N/A - 18 Years

Genders Eligible for Study


Not currently accepting new patients for this trial

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Thomas J Caruso, M.D., M.Ed.