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The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)
Not Recruiting
Trial ID: NCT03882788
Purpose
The purpose of this study is to assess whether the type of anesthesia, narcotic-based versus
inhalational anesthesia administered during cardiopulmonary bypass (CPB) surgery contributes
to the wide variation in neurologic recovery and developmental outcome after surgery in
infants with congenital heart disease.
Official Title
Anesthesia and the Developing Brain: a Comparison of Two Anesthetic Techniques
Stanford Investigator(s)
Eligibility
Inclusion Criteria:
- Neonates of at least 32 weeks of gestation, infants and children up to 2 years of age
admitted to The Children's Hospital for treatment of cyanotic or non-cyanotic heart
disease requiring surgical intervention.
- Admitting diagnosis of cyanotic or non-cyanotic heart disease
Exclusion Criteria:
- Neonates less than 32 weeks of gestational age, and children more than 2 years of age.
- Any documented central nervous system malformations.
- Any potential subject requiring unexpected postoperative Extracorporeal membrane
oxygenation (ECMO) support
Intervention(s):
drug: Isoflurane
drug: Fentanyl (high dose)
drug: Fentanyl (low dose)
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305