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Composite Health Assessment Risk Model (CHARM) for Older Adults (BMT CTN 1704)
Not Recruiting
Trial ID: NCT03992352
Purpose
Prospective observational multicenter study of allogeneic Hematopoietic Stem Cell
Transplantation (HCT) in recipients 60 years and older to assess important determinants of
health status to be combined into a composite health risk model to improve risk assessment of
non-relapse mortality (NRM).
Official Title
Composite Health Assessment Risk Model (CHARM) for Older Adults: Applying Pre-Transplant Comorbidity, Geriatric Assessment, and BioMarkers on Non-Relapse Mortality After Allogeneic Transplant (BMT CTN 1704)
Stanford Investigator(s)
Laura Johnston
Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy)
Eligibility
Inclusion Criteria:
1. Subject is > 60.0 years old at time of enrollment.
2. Hematological malignancy as an indication for allogeneic transplantation.
3. Eligible for allogeneic transplantation based on institutional standards
4. First allogeneic transplant planned. Any conditioning regimen and allogeneic donor is
acceptable.
5. Able to speak and read English. Spanish, and Mandarin will be acceptable when sites
have ability to perform healthcare provider tests in those languages.
6. Written informed consent
Exclusion Criteria:
1. Prior allogeneic HCT
Intervention(s):
diagnostic test: Age 60+ with planned HCT for Hematologic Malignancy
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Melanie Gaudinez
650-725-4983