Immunophenotyping Assessment in a COVID-19 Cohort

Inclusion Criteria:

Individuals who meet all of the following criteria are eligible for enrollment as study
participants:

   - Participant and/or surrogate understands the data to be collected and the study
   procedures and is willing to participate in the surveillance cohort as described in
   the study information sheet;

   - ≥ 18 years of age at the time of hospitalization; and

   - Admitted to a hospital with presumptive or documented coronavirus disease 2019
   (COVID-19), with confirmation of Severe Acute Respiratory Syndrome Coronavirus-2
   (SARS-CoV-2) infection by Polymerase Chain Reaction (PCR).

Exclusion Criteria:

Individuals who meet any of these criteria are not eligible for enrollment as study
participants:

   - Underlying medical problems which, in the opinion of the investigator may be
   associated with mortality unrelated to COVID-19 within 48 hours of hospitalization, or
   a decision by the patient or surrogate prior to hospitalization to limit care to
   comfort measures; or

   - Medical problems or conditions such as pregnancy which might impact interpretation of
   the immunologic data obtained.