Breath Metabolomics in the Laboring Parturient

Not Recruiting

Trial ID: NCT04564196

Purpose

This is primarily a feasibility study to determine whether quantitative measurement of volatile organic compounds (VOCs) in the breath of parturients undergoing labor is possible. Aim A: To determine baseline values of breath metabolites and volatile organic compounds (VOCs) in the breath for term pregnant women. Aim B: To gather preliminary data to determine breath metabolite and volatile organic compound (VOCs) signature change during labor and delivery. Aim C: Compare the breath metabolite and volatile organic compound (VOCs) signature women undergoing induction compared to spontaneous vaginal deliveries.

Official Title

Feasibility Study of the Collection of the Breath Metabolome From Healthy Parturients During Labor

Stanford Investigator(s)

Cedar Fowler

Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine

Pervez Sultan

Professor of Anesthesiology, Perioperative and Pain Medicine

Eligibility


Inclusion Criteria:

   - Otherwise healthy nulliparous women with singleton term (37-41 weeks) pregnant at
   least 18 years of age.

   - Presenting for labor (induction of labor and spontaneous labor) at LPHC.

Exclusion Criteria:

   - Participants unable to or refuse to give informed consent

   - Participants that do not understand English or are hearing impaired

   - Medical History: Chronic disease (HTN, diabetes, asthma)

   - Obstetric History during this pregnancy: gestational diabetes, gestational
   hypertension, pre-eclampsia, Eclampsia

   - Multiple gestation

   - Any significant fetal anomalies

   - Morbid obesity (BMI>50)

Intervention(s):

procedure: Breath Sample

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305