Trial Search Results

COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C

The primary objectives of this study are:

- To determine the proportion of children with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) related death, rehospitalization or major complications after infection with SARS-CoV-2 and/or Multisystem Inflammatory Syndrome in Children (MIS-C), and

- To determine immunologic mechanisms and immune signatures associated with disease spectrum and subsequent clinical course during the year of follow-up.

Stanford is currently accepting patients for this trial.

Lead Sponsor:

National Institute of Allergy and Infectious Diseases (NIAID)

Collaborator: Autoimmunity Centers of Excellence

Stanford Investigator(s):

Intervention(s):

  • Other: SARS-CoV-2 and/or MIS-C Exposure

Eligibility


Inclusion Criteria:

   1. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) detection from a
   respiratory specimen, and/or

   2. Meets criteria for Multisystem Inflammatory Syndrome in Children (MIS-C), and/or

   3. Meets criteria for MIS-C, except has involvement of only 1 organ system

Cases meeting clinical criteria for MIS-C but without known SARS-CoV-2 exposure, and who
are being treated as MIS-C by the treating physician, but with negative SARS-CoV-2 PCR and
pending or negative antibody testing, may be enrolled as subjects. If subsequent antibody
testing is positive, cases will be labelled as confirmed MIS-C. If SARS-CoV-2 antibody
testing is negative, subjects will be labeled at the end of the study as suspected/not
confirmed MIS-C.

Exclusion Criteria:

1. Subject and/or parent/guardian who are not able to understand or be willing to provide
informed consent and where applicable assent

--Note, for this observational cohort study, participation in other COVID-19 studies is not
an automatic exclusionary criterion.

Ages Eligible for Study

N/A - 20 Years

Genders Eligible for Study

All

Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Olivia Martinez
650-498-6247
Recruiting