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The Effect of Micro Fragmented Adipose Tissue (MFAT) on Shoulder Osteoarthritis
Recruiting
I'm InterestedTrial ID: NCT04929951
Purpose
This is a non-surgical trial comparing the clinical and functional outcomes of patients with
osteoarthritis treated with Intra-articular injection of Micro Fragmented Adipose Tissue
versus conventional therapy of intra-articular injection of corticosteroid.
Official Title
The Effect of Micro Fragmented Adipose Tissue (MFAT) on Shoulder Osteoarthritis
Stanford Investigator(s)
Geoffrey Abrams, MD
Associate Professor of Orthopaedic Surgery
Eligibility
Inclusion Criteria:
- Age between 25 and 75 years-old
- Diagnosis of pre-existing osteoarthritis of the glenohumeral joint
- Working understanding of the English language and able to fully understand the
procedure
- Capable of providing informed consent
- Able to complete online, in-person or phone surveys for the purposes of follow-up
- Capable of understanding pre- and post-procedure care instructions
- Ambulatory at baseline
- Previous trial and failure of conservative therapy consisting of a minimum of 6 weeks
of physical therapy and trial of anti-inflammatory medications if not contraindicated,
with or without concomitant bracing and/or injections.
Exclusion Criteria:
- Age < 25 or > 75 years old
- Radiographs demonstrating either no, little osteoarthritis, severe(bone on bone)
osteoarthritis
- Prior total or partial joint replacement surgery or surgery involving cartilage
regeneration
- Previous cortisone, PRP or Hyaluronic acid intra-articular injection within the last 3
months
- Co-morbidity with the rheumatologic condition, inflammatory arthritis
- Currently undergoing immunomodulatory therapy
- Uncontrolled endocrine disorder
- BMI >40 or joint space not visible by ultrasound
- Current diagnosis of osteomyelitis, human immunodeficiency virus (HIV-1, -2) and/or
hepatitis C (HCV), infection, and poorly controlled diabetes (HgA1C >7.0)
- Pregnancy or planned pregnancy
- previous stem cell injection into treatment joint
- Patient scheduled to undergo any concomitant shoulder surgical procedures or other
surgery which may affect outcomes.
- Coagulopathy or anticoagulant treatment
- Chronic pain involving multiple body parts or opioid medication management
- Diagnosis of fibromyalgia
- Concomitant massive(2 tendons with retraction), complete rotator cuff tendon tear
Intervention(s):
biological: Micro Fragmented Adipose Tissue
biological: Corticosteroid injection
Recruiting
I'm InterestedContact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Shannon Schultz, BA
650-723-2897