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Picture of Incidental Calcium To Understand Risk Estimate (PICTURE) Trial
Recruiting
I'm InterestedTrial ID: NCT05588895
Purpose
This is a prospective randomized controlled trial assessing the impact of notifying patients
and their clinicians of an incidental finding of coronary artery calcification (CAC)
indicating increased cardiovascular risk. Patients will be identified through completed
radiology orders for non-gated, non-contrast chest CT in the appropriate clinical context and
then will have an EHR screen for inclusion criteria. The presence of CAC will be confirmed by
a board-certified physician. Eligible patients will be randomized to CAC notification or
usual care using a 1:1 stratified block randomization method based on baseline statin use.
Official Title
NOTIFY 2: Picture of Incidental Calcium To Understand Risk Estimate
Stanford Investigator(s)
Fatima Rodriguez
Associate Professor of Medicine (Cardiovascular Medicine)
Eligibility
Inclusion Criteria:
- Age 18 and above and <85
- Non-gated chest CT with CAC
- An encounter after January 1, 2020 with a Stanford-affiliated clinician from one of
the following clinics:
- Stanford Internal Medicine (includes University affiliated clinics)
- Stanford Family Medicine (includes University affiliated clinics)
- Non-EP cardiologist
Exclusion Criteria:
- Advanced or poor-prognostic cancer
- No active primary care at Stanford Health Care
- Age <18 or >85
- Non-English or non-Spanish speaking
- Baseline statin or non-statin lipid lowering therapy
- Allergy to statin medication or identification of statin-associated muscle symptom
Intervention(s):
other: Notification
Recruiting
I'm InterestedContact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Fatima Rodriguez
650-497-0881