Current Research and Scholarly Interests
Our research group integrates new molecular technology development, advanced computation methods and genome biology to identify targets for therapy in cancer. We are pursuing projects focused on developing new therapies for stomach, bile duct and colon cancer. We also are involved in study the basis of genomic instability by examining chromosome structure.
Ongoing projects include:
1) Immunogenomic approaches to study cancer's interaction with the immune system and improve our understanding of immunotherapy
2) Identification of kinase interactions which can improve targeted therapy strategies
3) Use of advanced genome sequencing technologies including nanopore sequencers to understand the role of cancer rearrangements in response to therapy
4) Identifying genes that increase the risk of developing cancer
5) Developing new approaches for monitoring cancer from circulating DNA
We are developing new technologies for data storage using DNA technologies.