John R. Adler, MD

The Dorothy and Thye King Chan Professor in Neurosurgery, Emeritus

Academic Appointments

Emeritus Faculty - University Medical Line, Neurosurgery

Administrative Appointments

CEO, Zap Surgical Systems (2015 - 2017)
CEO & Chairman, Cureus, Inc (2010 - 2017)
CEO, Accuray, Inc. (1999 - 2002)
Chief of Clinical Innovation, Varian Medical Systems, Inc (2009 - 2015)
Chairman, Accuray, Inc. (1999 - 2004)
Vice President, Western Neurosurgical Society (2005 - 2006)
President, Cyberknife Society (2003 - 2008)
Founder and Member of the Board of Directors, Accuray, Inc. (1991 - 2009)

Honors & Awards

The Inaugural Ideals of Entrepreneurship Award, Emerging Entrepreneurs in Biomedical Technology, Biodesign Group, Stanford University (2005)
Outstanding Achievement in Medicine, Santa Clara Valley Medical Association (2007)
The Cushing Award for Excellence and Innovation in Neurosurgery, The American Association for Neurological Surgery (2018)
The Thomas Fogarty Lecture, The Stanford Byers Center for Biodesign and The Fogarty Institute for Innovation (2018)

Professional Education

MD, Harvard University, Medicine (1980)
AB, Harvard College (1976)

Current Research and Scholarly Interests

The development and implementation of computerized, image-guided surgical tools to be utilized during minimally invasive brain operations. The clinical outcome of new technologies, and in particular the application of radiosurgery, for the treatment of brain tumors. The creation of new radiosurgical techniques for a wide array of brain and spine disorders which includes 1) trigeminal neuralgia 2) spinal cord AVM 3) pituitary tumors 4) skull base meningioma 5) benign peri-optic tumors 6) brain metastases 7) acoustic neuroma 8) glomus jugulare tumors 9) brain and spine schwannoma 10) painful facet syndrome 11) radiomodulation for functional disease of the brain

Clinical Trials

Study of Fractionated Stereotactic Radiosurgery to Treat Large Brain Metastases Not Recruiting
More
The maximum tolerated dose of 3-session (ie, treatment) stereotactic radiosurgery (SRS) to treat brain metastases greater than 4.2 cm³ in size will be determined. This study investigates if increasing radiation dose improves outcome for patients without greater toxicity (side effects).

Stanford is currently not accepting patients for this trial. For more information, please contact Polly Young, 650-497-7499.

Lead Sponsor
- Stanford University
Stanford Investigators
View full details
Radiosurgical Neuromodulation for Refractory Depression Not Recruiting
More
This study is designed to evaluate the safety and effectiveness of an investigational procedure for treating people with treatment resistant bipolar depression (TRD). Precise dose delivery of radiation to the predetermined targets in the brain will be accomplished with known Cyberknife stereotactic radiosurgery methods. This technology is considered to be noninvasive (does not physically invade your body). We will be studying if the Cyberknife influences the sensitivity of certain nerves of your brain. Although many clinical treatments for psychiatric conditions have been done using stereotactic radiosurgery, the present study is experimental, because we are seeking to use more moderate doses of radiation that are intended not to destroy any brain cells, but to normalize or modulate their function.

Stanford is currently not accepting patients for this trial. For more information, please contact Jessica Hawkins, 6507238323.

Lead Sponsor
- Stanford University
Stanford Investigators
View full details

2023-24 Courses

Independent Studies
- Directed Reading in Neurosurgery
  NSUR 299 (Sum)
- Early Clinical Experience in Neurosurgery
  NSUR 280 (Sum)
- Graduate Research
  NSUR 399 (Sum)
- Medical Scholars Research
  NSUR 370 (Sum)
- Undergraduate Research
  NSUR 199 (Sum)

All Publications

Profiles With Related Publications

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Patrick Barnes

Professor of Radiology (Pediatric Radiology) at the Stanford University Medical Center, Emeritus
Research Interests
Advanced imaging, including magnetic resonance imaging, of injury to the developing central nervous system; including fetal, neonatal, infant and young child; and, including nonaccidental injury (e.g. child abuse).

See Biosketch for details.

193 Total Publications
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Steven D. Chang, MD

Robert C. and Jeannette Powell Neurosciences Professor and, by courtesy, of Otolaryngology - Head & Neck Surgery (OHNS) and of Neurology
Clinical Focus
Cancer > Neuro Oncology, Brain / Central Nervous System Tumors, Brain / Central Nervous System Tumors - Neuro Oncology, Brain / Central Nervous System Tumors - Neurosurgery, Neurological Surgery, Neurosurgery, Skull Base Tumors , Skull Base Tumors - Head and Neck Surgery, Spinal Cancer, Spinal Cancer - Neurosurgery, Spinal Cancer - Surgery, Acoustic Neuroma, Glioma, Astrocytic, Glioma, Glioblastoma, Glioblastoma with Sarcomatous Component, Astrocytoma, Ependymoma, Medulloblastoma, Meningioma, Intracranial Aneurysm, Carotid Stenosis, Arteriovenous Malformations, Intracranial Arteriovenous Malformations, ACTH-Secreting Pituitary Adenoma, Adenoma, Prolactin-Secreting, Pituitary, Diabetes Insipidus, Pituitary, Growth Hormone-Secreting Pituitary Adenoma, Hypothalamic-Pituitary Neoplasms, Neoplasms, Hypothalamic-Pituitary, PRL-Secreting Pituitary Adenoma, Pituitary ACTH Hypersecretion, Pituitary ACTH-Producing Cells, Pituitary ACTH-Secreting Cells, Pituitary Adenoma, Prolactin-Secreting, Pituitary Adrenocorticotropin-Secreting Cells, Pituitary Apoplexy, Pituitary Diseases, Pituitary FSH Hypersecretion, Pituitary Gland, Pituitary Growth Hormone-Secreting Cells, Pituitary Irradiation, Pituitary Neoplasms, Prolactin-Producing Pituitary Adenoma, Prolactin-Secreting Pituitary Adenoma, Vestibular Schwannoma, brain metastasis, Cyberknife, Radiosurgery, Stereotactic, Stereotactic Techniques, spinal avm, spinal tumor, Spinal Meningioma, spinal schwannoma, Trigeminal Neuralgia, Hemifacial Spasm, Glossopharyngeal Nerve Diseases, AVM (Arteriovenous Malformation) Intracranial, Stroke, Brain Tumor, Primary, Brain Tumor, Recurrent, Brain Tumors, Malignant Primary Brain Tumors, Primary Malignant Brain Tumors, Aneurysm, Cerebral, Acoustic Neuroma, Cerebellopontine Angle, Aneurysm, Anterior Cerebral Artery, Aneurysm, Middle Cerebral Artery, Aneurysm, Posterior Cerebral Artery, Anterior Cerebral Artery Aneurysm, Cerebral Cavernous Hemangioma, Cerebral Hemorrhage, Cerebral Vasculitis, Middle Cerebral Artery Aneurysm, Posterior Cerebral Artery Aneurysm, Vascular Malformations, Brain, Brain Aneurysm, Brain Neoplasms, Brain Revascularization, Neurogenetics, Neuroprotenomics, Neurocutaneous Syndromes, Glomus Tumor, Craniopharyngioma, Pituitary tumor
Research Interests
Clinical research includes studies in the treatment of cerebrovascular disorders, such as aneurysms and AVMs, as well as the use of radiosurgery to treat tumors and vascular malformations of the brain and spine.

Dr. Chang is C0-Director of the Cyberknife Radiosurgery Program.

Dr. Chang is also the head of the The Stanford Neuromolecular Innovation Program with the goal of developing new technologies to improve the diagnosis and treatment of patients affected by neurological conditions.

340 Total Publications
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Cynthia Chuang

Clinical Professor, Radiation Oncology - Radiation Physics

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Huy M. Do, MD

Professor of Radiology (Neuroimaging and Neurointervention) and, by courtesy, of Neurosurgery and of Otolaryngology - Head & Neck Surgery (OHNS)
Clinical Focus
Interventional Neuroradiology, Endovascular Neurosurgery, Cerebral aneurysm coiling, Brain AVM (arteriovenous malformation), Stroke, Spinal Intervention for pain, Head and neck vascular malformations and anomalies, Interventional Oncology, Pediatric Neuroradiology, Vascular Malformations, Percutaneous Sclerotherapy, Vertebral compression fractures, Trigeminal Neuralgia and facial pain, Neuroradiology

161 Total Publications
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James R. Doty, M.D.

Adjunct Professor, Medicine - Primary Care and Population Health
Research Interests
My interest for many years has focused on neuro-oncology (brain tumors) and utilizing both surgery and stereotactically focused radiation to treat solid tumors of the nervous system primarily utilizing the CyberKnife.

In addition, I am an expert in complex and minimally invasive spine surgery.

More recently, my interests revolve around understanding the neural, social and mental bases of compassion and altruism using a multi-disciplinary approach.

21 Total Publications
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Nancy Fischbein

Professor of Radiology and, by courtesy, of Otolaryngology - Head & Neck Surgery (OHNS) , of Neurology, of Neurosurgery & of Radiation Oncology
Clinical Focus
Diagnostic Neuroimaging

215 Total Publications
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Paul Graham Fisher, MD

Beirne Family Professor of Pediatric Neuro-Oncology, Professor of Pediatrics and, by courtesy, of Neurosurgery and of Epidemiology and Population Health
Clinical Focus
Cancer > Neuro Oncology, Neurology - Child Neurology, Neuro-Oncology, Neurology
Research Interests
Clinical neuro-oncology: My research explores the epidemiology, natural history, and disease patterns of brain tumors and other cancers in childhood, as well as prospective clinical trials for treating these neoplasms. Research interests also include neurologic effects of cancer and its therapies.

276 Total Publications
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Iris C. Gibbs, MD, FACR, FASTRO

Professor of Radiation Oncology (Radiation Therapy) and, by courtesy, of Neurosurgery
Clinical Focus
Cancer > Radiation Oncology, Brain / Central Nervous System Tumors - Radiation Oncology, Cyberknife/radiosurgery, Acoustic Neuroma , Pediatric brain tumors, Health Equity, Cancer Health Equity, Spinal Cancer - Radiation Oncology, Brain / Central Nervous System Tumors, Pediatric Cancers, Leptommeningeal Disease, Leptommeningeal Disease - Radiation Oncology, Pituitary Adenomas, Pituitary Adenomas - Radiation Oncology, Radiation Oncology, Skull Base Tumors , Skull Base Tumors - Radiation Oncology, Spinal Cancer, Radiosurgery
Research Interests
Dr. Gibbs is a board-certified radiation oncologist who specializes in the treatment of CNS tumors. Her research focuses on developing new radiation techniques to manage brain and spinal tumors in adults and children. Dr. Gibbs has gained worldwide acclaim for her expertise in Cyberknife robotic radiosurgery.

174 Total Publications
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Seunggu Jude Han, MD

Clinical Associate Professor, Neurosurgery
Clinical Focus
Neurological Surgery

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Steven Hancock, MD

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Melanie Hayden Gephart

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Robert K. Jackler, MD

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Neurotology
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